$\displaystyle{\sum_{k=2}^{n} \frac{1}{k}}$  can never be an  integer for any value of $n$.
Firstly, observe that among the natural numbers from 2 to $n$ there is exactly one natural number which has the highest power of 2 as its divisor. Now, while summing up the reciprocals of these natural numbers we will get a fraction as the answer. In that fraction, the denominator will be an even number since it’s the least common multiple of all numbers from 2 to $n$. And the numerator will be an odd number since it’s the sum of $(n-2)$ even numbers with one odd number (corresponding to the reciprocal of the number with the highest power of 2 as the factor). Since under no circumstances an even number can completely divide an odd number, denominator can’t be a factor of the numerator. Hence the fraction can’t be reduced to an integer and the sum can never be an integer.